Nexium/Nexium IV Indications/Uses

Gastroesophageal Reflux Disease (GERD): treatment of erosive reflux esophagitis; long-term management of patients with healed esophagitis to prevent relapse; symptomatic treatment of gastroesophageal reflux disease (GERD).
Nexium: Tablet: Esomeprazole (NEXIUM) tablets are indicated for: Patients requiring continued non-steroidal anti-inflammatory (NSAID) therapy: treatment of upper gastrointestinal symptoms associated with non-steroidal anti-inflammatory drug (NSAID) therapy; healing of gastric ulcers associated with non-steroidal anti-inflammatory drug (NSAID) therapy, including COX-2 selective NSAIDs; prevention of gastric and duodenal ulcers associated with non-steroidal anti-inflammatory drug (NSAID) therapy, including COX-2 selective NSAIDs, in patients at risk.
Patients requiring continued low dose aspirin (75-325 mg) therapy: prevention of gastric and/or duodenal ulcers associated with low dose aspirin therapy, in patients at risk.
Following treatment with Esomeprazole (NEXIUM) IV: Maintenance of hemostasis and prevention of rebleeding of gastric or duodenal ulcers.
In combination with an appropriate antibacterial therapeutic regimen for the eradication of Helicobacter pylori and; healing of Helicobacter pylori associated duodenal ulcer and; prevention of relapse of peptic ulcers in patients with Helicobacter pylori associated ulcers.
Pathological hypersecretory conditions including Zollinger-Ellison syndrome and idiopathic hypersecretion.
Granules: Esomeprazole (NEXIUM) oral suspension is primarily indicated for GERD in children 1-11 years old.
Esomeprazole (NEXIUM) oral suspension may also be used by patients having difficulty swallowing dispersed Esomeprazole (NEXIUM) tablets. For indications in patients from the age of 12 years reference is made to the Esomeprazole (NEXIUM) Tablet Prescribing Information.
Nexium IV: Esomeprazole (NEXIUM) I.V. is indicated as an alternative where oral therapy is not appropriate. I.V. therapy would constitute only part of a full treatment period for the following indications: Adults: Patients requiring continued non-steroidal anti-inflammatory (NSAID) therapy: for healing of gastric ulcers associated with NSAID therapy; for prevention of gastric and duodenal ulcers associated with NSAID therapy, in patients at risk.
Esomeprazole (NEXIUM) I.V. is indicated for the short-term maintenance of hemostasis and prevention of rebleeding in patients following therapeutic endoscopy for acute bleeding gastric or duodenal ulcers.
Children and adolescents aged 1-17 years: gastric antisecretory treatment when the oral route is not possible, such as: gastroesophageal reflux disease (GERD) in patients with erosive reflux esophagitis and/or severe symptoms of reflux.